Amino Acids

The deluge of dietary supplements on the market today provides countless avenues for the fitness enthusiast to achieve their goals. Rather than drawing into a fitness lifestyle through proper nutrition, exercise, and rest, many will turn to dietary supplements as a panacea for all their fitness dreams. With all of the misinformation and empty promises that accompany many products, trying to keep afloat on all of the new breakthroughs can be overwhelming. Protein powders are the original bodybuilding supplement and continue to be a staple in the bodybuilders diet. Unfortunately, many fitness enthusiasts and bodybuilders' love and devotion to protein far surpass their knowledge of how protein works in the body. Why do so many fitness enthusiasts have such a limited understanding of protein and amino acids? We hope that the information in this article will serve as a beacon among the sea of misinformation about protein and amino acids. The ultimate value of a food protein or a protein supplement is in its amino acid composition. Amino acids are the building blocks of protein, and muscle tissue. Many physiological processes relating to bodybuilding from energy, recovery, muscle hypertrophy, fat loss, and strength gains are linked to amino acids. The twenty-three amino acids are the molecular building blocks of protein. The amino acids can be divided into two groups: essential amino acids and non-essential amino acids. The nine essential amino acids are so designated because they must be supplied by the foods we eat. The twelve non-essential amino acids are so designated based on the body ability to synthesize them from other amino acids.
The Different Amino Acids
Essential Amino Acids Nonessential Amino Acids
Histidine Alanine
Isoleucine Arginine
Leucine Aspartic Acid
Lysine Cysteine
Methionine Cystine
Phenylalanine Glutamic Acid
Tryptophan Glutamine
Valine Glycine
Threonine Proline
Serine
Tyrosine
How The Body Handles Protein
The fate of an amino acid after it is transported to the liver is highly dependent on the body needs for that moment. Some amino acids enter the blood stream, where they join amino acids that have been liberated during the constant breakdown and synthesis of body tissue. Other amino acids are used by the liver to manufacture many of the specialized proteins such as liver enzymes, lipoproteins, and the blood protein (albumin). As these amino acids circulate throughout the body, each cell directed by its own DNA blue print, draws from the common pool of available amino acids to synthesize all the numerous proteins required for its functions. In order for protein synthesis to occur, an adequate supply of both essential and non-essential amino acids is vital. If one of the essential amino acids is missing then synthesis is halted. These partially assembled proteins are disassembled and the amino acids returned to the blood. Any amino acids that are not used within a short time can not be stored for future use. They are delivered back to the liver and stripped of their nitrogen. Which is then incorporated into urea and excreted by the kidneys. The remaining protein skeleton will be converted to glucose and burned as energy or converted to fat or glycogen for storage. Although protein synthesis is very important, the body number one priority is to obtain sufficient energy to carry on vital functions such as circulation, respiration and digestion. Therefore, in the absence of adequate dietary carbohydrates and fat calories, the body will break down not only dietary protein but protein in the blood, liver, pancreas, muscles, and other tissues in order to maintain vital organs and functions.
Applications To Bodybuilding
As we have already discussed, the fate of an amino acid after it is transported to the liver is highly dependent upon the body needs at that moment. Immediately after exercise, when the muscle is receptive to nutrients and the blood flow to the exercise muscles remain high; a window of opportunity exists to aid muscular growth and recovery. Unfortunately, a high protein meal will not put significant levels of amino acids into your blood stream until a couple of hours after you eat it, especially if blood flow to the gastrointestinal tract has been diminished by a hard training sessions. The most reliable way to deliver specific amino acids is to administer the particular amino acids themselves through free form amino acids. The value of free form amino acids is first and foremost is that they do not require digestion. They are free of chemical bonds to other molecules and so move quickly through the stomach and into the small intestine, where they are rapidly absorbed into the bloodstream within fifteen minutes. This quick absorption helps prevent muscle catabolism. Without sufficient energy, the human body as discussed above, has the innate ability to break down muscle tissue for use as an energy source during heavy exercise. This process is known as gluconeogenesis, which is the production of glucose from non-carbohydrate sources. The part of the reaction that pertains to our discussion is known as the glucose alanine cycle. During this cycle, BCAAs (three of the essential amino acids: leucine, isoleucine, and valine) are stripped from the muscle tissue and parts of them are converted to the amino acid alanine, which is transported to the liver and converted to glucose. Branched-chained amino acids are metabolized directly in the muscle and can be converted into energy to prevent muscle catabolism. If you supplement with BCAAs the body does not have to break down muscle tissue to derive extra energy. A study conducted at the School of Human Biology, University of Guelph, Ontario, Canada, confirmed that the use of BCAAs (up to 4 grams) during and after exercise could result in a significant reduction of muscle breakdown during exercise. Amino acids are truly the building blocks of muscle tissue and protein. We hope that the article clarifies the importance of amino acid supplementation to your diet as well as reinforce amino acids many physiological contributions to bodybuilding.

Shoulders Pain

Shoulders receive the lion's share of work in the gym. Nearly all upper body routines involve the shoulder to some extent, if only to be held fixed and motionless for the specific movement. Even during leg work, the shoulders are involved with the stacking and unstacking of plates for all the leg routines. Shoulder pain can greatly hamper any training routine and tends to require long periods of time for complete recuperation. Severe injuries can prematurely terminate the careers of professional athletes such as baseball pitchers with rotator cuff problems. For the non-professional athlete, even minor shoulder pain can lead to disturbed sleeping patterns from the inability to find a comfortable position at night. Part I of this two part series will examine shoulder anatomy in sufficient detail to highlight the basis for skeletal variations that can predispose certain individuals to persistent shoulder problems. Part II will go on to present routines for strengthening lesser known shoulder muscles and lifting variations to minimize further trauma. Bear in mind that severe pain, extreme muscle weakness, or inability to perform certain movements may indicate a condition requiring medical attention. Advice presented here should not serve in place of a thorough medical evaluation since certain conditions may require specialized medical intervention or even surgery. Due to its extremely wide range of mobility, the shoulder is one of the most complex joints in the human body. Because of its unusual bone structure and large number of muscle attachments, shoulder pain can be a daunting challenge to most physicians who typically recommend merely rest and anti-inflammatory medications for weeks to months as therapy which may or may not solve the problem. In addition, chronic degenerative changes that accumulate from repeated trauma will likely increase the frequency of shoulder problems for most individuals as they age and continue lifting. While any single article can hardly be exhaustive on the subject of shoulder issues (whole books 16,17 have been devoted to the subject), this discussion will focus on one of the more common problems that results from a combination of unlucky anatomy, undesirable lifting technique, and insufficient attention to auxiliary musculature. The shoulder is the anatomical structure that links the arm with the torso. A wide array of muscles of particular interest to bodybuilders traverse the shoulder including: pecs, lats, delts, and even the biceps. Given that the lats and delts contribute to a wide upper body desirable by bodybuilders, much attention is focused on these muscle groups and considerable stress is applied to the shoulder. Pain and discomfort can dramatically compromise nearly any weightlifting routine. The shoulder as a joint is classically described as a ball and socket (similar in design to the hip joint)1. The ball portion is derived from the end of the upper arm bone, the humerus, and resembles a ball stuck on the end of a long shaft, and is referred to as the humeral head. The socket side is formed from one corner of a roughly triangular flat bone called the shoulder blade (the scapula), that rests over the rib cage, high on the back and extends over the rib cage to the front of the body. The triangular form of the scapula has one side close to the midline of the back with the lower corner angling up towards the shoulder. The third side of the triangle runs parallel to the shoulders across the top. The shoulder blade is thicker in its upper portion than the lower portion, so that the very top of the shoulder blade has a surface (rather than just as edge as with the other two sides of the triangle) with two edges (one towards the body and one away). The top edge pointing away from the body is called the spine and the surface of the top of the shoulder blade is slightly depressed and called the supraspinous fossa (fossa is the technical term for a depression). Moving along the spine towards the shoulder, a bony extension, called the acromion, juts out and arches over the top of the scapula just above the humeral head and can be felt as the bony top of the shoulder. The acromion arches over the top of the scapula from back to front and connects to the collarbone (clavicle) to complete the shoulder girdle. Arising off the top edge opposite the spine, also at the shoulder, across from where the acromion begins and pointing forward over the chest, is a small bony knob called the coracoid process. The short head of the biceps muscles attaches to this piece of bone as well as a small muscle called coracobrachialis and the pectoralis minor muscle (underneath pectoralis major, the main 'pecs'). In addition, a tough ligament connects the coracoid process with the acromion. The socket portion of the scapula that contacts the humerus is called the 'glenoid fossa,' but rather than looking like a true socket, the glenoid fossa is more open with the appearance of a saucer or rather like a golf tee with the humeral head as the golf ball. The reason for the openness is to permit a large range of motion in the joint. The downside to this large range of motion is the propensity of the shoulder to dislocate. A dislocation occurs when the humeral head moves beyond the confines of the glenoid fossa and slips over the lip of the saucer (your golf ball falls off the tee). When any muscle acts across a joint, opposing muscles are contracted as well to stabilize the joint. Imbalances in strength between opposing muscles can potentially lead to injuries. With the shoulder, the anatomy is not as simple as a one dimensional joint (such as the elbow). Movement of the shoulder requires many different muscles to create the movement as well as other muscles to stabilize the shoulder joint. In addition, since the shoulder blade is only attached (by other bones) to the upper arm and collar bone at one end, the blade portion must be held fixed by additional muscles. For example, serratus anterior (best seen in a well muscled, lean individual) is a small group of muscles that arises from the rib cage in front just below the pecs with the muscle bellies extending up and around to the back and disappearing underneath the lats. Serratus anterior attaches to the scapula along the edge closest to the middle of the back. Serratus's job is to prevent the shoulder blade from winging during shoulder movements; in other words, serratus pins the scapula to the back and so serves to stabilize the joint during movements. As discussed above, the shoulder joint has an extremely wide range of motion. A key structure supporting the shoulder joint is the rotator cuff. The rotator cuff is concerned with two major functions, rotating the shoulder and cuffing the joint 5,34. Rotation may not appear as an obvious movement with regard to the shoulder. To visualize shoulder rotation, place your arm at your side and bend the elbow to 90o, as if to shake hands, but maintain the upper arm against your side and keep you palm in (thumb up). Keeping your upper arm against your side, bring your forearm and hand across your body to rest your palm on your stomach. That movement is internal shoulder rotation (the upper arm bone, the humerus, is rotating relative to the shoulder; internal is used to denote a movement towards the midline of the body). A more extreme form of internal rotation is to place the back of your hand on the small of your back, again with your elbow bent at 90o. Now keeping your elbow bent, lift your hand away from your body. One muscle of the rotator cuff, subscapularis arises from the underneath side of the shoulder blade (the side against the rib cage) and attaches to the humerus in such a way as to produce rotation of the humerus when contracted. If the lifting of your hand away from your back produces extreme pain or is simply impossible to perform, injury to this muscle (or a tear in its tendon) may be the source. This problem requires medical attention. The opposite motion to internal rotation is external rotation (rotating your forearm away from your stomach with your upper arm against your side) and is produced by contracting two other muscles of the rotator cuff group, infraspinatus and teres minor. These muscles also arise from the shoulder blade, but on the outer side, and also attach to the humerus. These three muscles are responsible for shoulder rotation, but the rotator cuff complex has four muscles and this is where the cuff component is involved. The fourth muscle is called supraspinatus and arises over the top of the shoulder blade (in the supraspinous fossa) and crosses the shoulder joint traveling underneath the acromion and attaching to the humerus just below the humeral head. Altogether, these four muscles (the three true rotators and supraspinatus) are the innermost set of muscles surrounding the shoulder joint and form a cuff around the joint. Bearing in mind the shallow nature of the glenoid fossa and the propensity for the humeral head to dislocate, the contraction of all four muscles forms a tight wall around the lip of the socket to help hold the humeral head in position (centered in the glenoid fossa) 5. During almost any shoulder movement, these muscles are contracting to stabilize the joint throughout the movement by maintaining the humeral head centered in the glenoid fossa 34. When you throw an object, the entire movement is designed to throw your arm away from your body. The object is thrown because you release your grip on it. Your arm and shoulder joint stay in place because the rotator cuff is holding the upper arm bone in place. This is why rotator cuff injuries are so devastating to baseball pitchers; a strong, intact rotator cuff is needed to allow for high velocity pitches without injuring the shoulder joint. Weakness or worse, injury to the rotator cuff can place undue stress on the shoulder joint during heavy lifting routines (because the humeral head does not stay centered in the glenoid fossa). Strengthening the rotator cuff muscles, particularly the three involved with rotation is straightforward and basically involves movements as described above for internal and external rotation, but with light weights while lying on your side. The remaining muscle, the supraspinatus, is less straightforward and unfortunately, much advice over the years has served to compound problems 30, especially for those who are anatomically predisposed to have problems in the first place.

Fish Oil

Obesity is of increasing concern in health issues in the world, surpassed only by cancer and heart disease. Dietary fat is often implicated as the primary root cause of the prevalence of obesity in developed countries. However, research continues to mount that support all fat is not evil. While high intakes of saturated fat and cholesterol are highly correlated with obesity, insulin resistance and heart disease, other fats are gaining respect as actually attenuating these factors. The most favorable fat in recent research is fish oil.

What Are The Benefits?

The benefits of a diet comprised mostly of polyunsaturated fats are well documented. The essential fatty acids omega-3, 6, and 9 must be obtained from food sources. These fatty acids are the precursors for several classes of hormones and comprise most of our cell membranes. Studies are now suggesting that the omega-3 fatty acids are our friends in a number of ways. Since our modern diet typically is high in omega-6 fatty acids and low in omega-3 acids, it may prudent to increase our consumption of foods that contain a higher amount of omega-3 fatty acids. The richest source of omega-3 fatty acids is fish oil from cold water fish.
Omega-3 fatty acids improve insulin action and glucose metabolism in fat and muscle cells. The fatty acids in the phospholipid layer of cell membranes determine the physiochemical properties of the membranes. This in turn influences the cellular functions, especially hormone responsiveness. Increasing the membrane content of polyunsaturated fatty acids increases membrane fluidity and the binding of many hormones to their respective receptors, thereby increasing their action.
They also decrease plasma triglyceride levels. This is hypothesized and supported by studies to play a role in increasing insulin action. It involves fuel switching due to increased utilization of glucose. It is also thought that fish oil supplementation reduces insulin secretion.
Another important aspect is that a diet derived mostly of it fatty acids from fish oils (high 0-3:0-6/9) was shown to reduce white adipose tissue mass, or body-fat, significantly. This has been demonstrated repeatedly in rat models, and also in humans. While omega-3's also increased thermogenesis in brown adipose tissue in rats, that probably has less significance for humans. However, they have detected much lower levels of enzyme activity for fatty acid synthesis in fish oil fed rats (and in vitro human fat cells) than in those fed diets with omega-6, omega-9 and saturated fats. Rats fed diets with omega-3 lost more fat mass (and had much lower triglyceride levels) than those fed a low-fat, high carb diet that was matched for calories.
They have shown in both rats and humans that the composition of adipose fatty acids basically resembles the fatty acid composition of the diet. However, those eating diets high in fish oil EPA and DHA (omega-3's) were not stored in the adipose tissue in similar proportion to the concentrations in the diet. Therefore, these fatty acids may be preferentially oxidized and not stored. Thus, such rapid fatty acid oxidation might prevent a significant portion of lipid accumulation.
Other Benefits

The other positive benefit is the consumption of a diet high in 0-3 induced an increase in UCP2 in white adipose tissue. Increased UCP2 uncoupling is associated with reductions in body weight and white adipose tissue.
Interestingly, a reduction of leptin levels, the fat-stat hormone, was reported with high omega-3 consumption. However, as most of the researchers stated in these studies, this may be an artifact simply due to the reduction in fat mass (leptin is secreted by fat cells).
However, in the studies that reported this, they also demonstrated a sustained decrease in appetite and no change in energy expenditure concomitant with decreased leptin levels, which indicates that decreased leptin levels may not be a concern unless they become acutely low, such as in a lean person. In that case, rotation or a blend of fatty acid sources would be necessary. But considering that our diet typically contains a high ratio of o-6:o-3, that may still be a moot point.