Wednesday, May 9, 2012

Follistatin!


Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh). Follistatin Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 288 amino acids and having a total molecular mass of 31.5kDa. The FST is purified by proprietary chromatographic techniques.

Monday, May 7, 2012

IGF1


IGF-1 is naturally produced in the liver as a result of GH (Growth Hormone) metabolism in the presence of insulin. Muscle tissue can also produce IGF-1 by way of an intracellular response. In fact, one of the benefits of training sets that result in an intense burn, or stretch position training, is the production of natural IGF-1. It is also a side effect of oral 17-ALFA ALKYLATED STEROIDS, which cause a higher release of IGF-1 from the liver. IGF-1 receptors exist throughout muscles and organs such as the heart, spleen, small intestines, and kidneys with a higher concentration of receptors exerting effects upon organs. IGF-1 is extremely anabolic, far more so than GH or Insulin.

Sunday, May 6, 2012

What to look for in gym?

When looking for a gym or fitness center I believe you should ultimately go where to use couching knowledge and you feel the most comfortable or really what your gut instinct tells you. The following information is not meant to knock any fitness facility or gym. This info is for you, the reader, to help you spend your money the smartest and wisest ways possibly, especially in a tighter economy. None of us want to waste our hard-earned money at a fitness center where we are not getting a lot of product and service for our money. Where you choose to workout is your business and "to each his own". Whatever gets you moving and healthier is a great choice anyway. In the late 2006's after I received the coaching certificate the first job I had as a personal trainer was in Tehran, Iran. That job was with Bodybuilding and Fitness Center; at the time they only had 5 gyms (now they have nearly 40 gyms). The one I worked in was nearly 10,000 square meter and was always clean, with lots of equipment, free classes with membership, knowledgeable staff, and very reliable. I was the youngest personal trainer so I had to really work hard to market myself. One of the ways I did this was to take on another job with the same gym. The job I took was personal trainer, supplement and diet consultation. This meant taking the responsibilities of a trainer who helped all members with a few free sessions to get them integrated into the gym. This helped me increase my personal training business, but more importantly humbled me. I was humbled with the additional position because to do this job you also had to put back all of the weights that were left out on the floor or out of place each night, sometimes fill in at the front desk, call and confirm appointments, check on the status of new and existing members, and all kinds of other little jobs... all for about 4.00 Euros an hour. After my first job I was hired by the infomercial guy to train people One-On-One in one of his personal training facilities in Tehran and so and so… Move to Estonia! When I chose to move to Estonia at 2009 I also had to make a decision on a gym for me to workout in and also to present my best experiences and knowledge about coaching and sport supplements.first year only I collected all information about this field here in Estonia then I felt who is training seriously and professional then they need to use high quality supplements but there wasn’t in market that’s why I bring Universal and Ultimate Nutrition from united states to Estonia. I have been to a lot of bodybuilding and fitness centers already and based my decision in Estonia on my previous gym until now!I look at the gyms by different eyes and I see many things that 90% of owner’s gym don’t see it!there is sometimes so frail and sometimes so big thing that they should care and correct it if they would like to achievement on their job and if they don’t upgrade their knowledge all the times then always they will be 5 years retard than all other countries. Sometimes I see in gym there is young boys and girls,they have so good potential to grow so easy and they can be one of Estonian professional athlete and bring for country many shining medals and rise up the Estonian’s flag in international contest but unfortunately there is no body to recognition and find them to give opportunity and support! 5 Tips For Finding A Good Gym Here is a checklist you can use in searching for a fitness center: 1. Clean Facility: You want the facility to be cleaned regularly and have some type of cleaner on hand, near equipment, or in a storage area if need be. Some gyms I have been to have towels with the cleaning products - which are washed regularly - and other gyms have paper towels loosely placed throughout, or in dispensers around the facility. Remember though... no matter where you go you should always wash your hands regularly, and never touch your eyes, nose, or mouth without first washing your hands thoroughly with soap. 2. Equipment Variety: Any place you go should have a lot of fitness equipment variety for you to choose from. Many times while on vacation I have chosen the gym with the most equipment variety because I like to change my routines and exercises often. My body is never bored this way. If you sign up at a place with 10 pieces of equipment it is better than sitting on the couch, but you will soon go stale in your routines. This usually leads to boredom, which leads to dropping out. 3. Free Classes: If you go to a gym which offers classes - such as: aerobics, toning, sculpting, cycling, strength, cardio, abs and bun firming, or step - and they want you to pay separate then you should be alarmed. I have been to a lot of very nice high-dollar gyms in many different countries and do not ever remember seeing anyone have to pay extra. Now if you have a top expert or celebrity come to speak, hold a class, or workshop, that is totally different. Also you may have personal trainers or nutritionists hold classes in a gym for a fee because this is for their knowledge business. 4. Knowledgeable Staff: If you get to the front desk of a gym and there are only a few people on staff - barely over the age of 18 - and they are not well-trained (formally or informally) to help you get the fitness results you desire, then choose another gym. Some of us do not need a knowledgeable staff because we already have a game plan, but this is the minority of us. The majority of us will have questions and need a little guidance and assistance. You usually cannot get this from the young guy or girl behind the desk who works there just because they look like they are in shape or even some guys who trained some years. Getting yourself into shape and getting others into shape are two totally different ball games. If you see some bodybuilder it doesn’t mean this person is coach or reverse, coaching is only perfect knowledge. 5. Reliable: All too often, over the years, I have seen gyms rush into small and large towns and cities promising the world, only to really take your money and leave town. Many times you will see these gyms come into town with good marketing, but not good service once you are in the doors. You want a gym with a great track record of being open a long time. You want a gym with a history of being good to its members.You want a gym has real personal trainer who care about you if you do some exercise wrong. you want a gym that does not have a history of closing its doors after getting you signed-up for long-term contracts. If you have to sign-up for a long-term contract with a gym it usually means they want you to stay even if you do not want to. Conclusion many of the top gym chains around the country changed their model years ago to month-to-month memberships and I feel like that is what is right and fair to members. You want a gym that does not try to nickel and dime you and ask for service fees which are constantly hitting your pocketbook. You are at the gym to work on you, not on them! A gym can never please everyone, but if the majority of members are satisfied, then the gym is doing something right.